Evolve Water and Insect I as soon as you possibly can. With all the genes unlocked, start up a Bacteria run on Mega-Brutal. This is by far the fastest and easiest way to unlock all of your genes, so we can get to the fun stuff. Each time, you'll get yourself another gene. Keep waiting out for those last few people to die, ending the game. Start evolving your kill symptoms now, (the ones that increase the "lethality" bar in the evolution screen) and wait until there are very few people left alive. Since you don't have the additional genes unlocked, just play this game to get used to the way things operate and how it works. When the game starts, the only disease type you'll have available is Bacteria. After unlocking one of those, another tier may be available to purchase (II, III, etc). Abilities are things that make your disease tougher and more adaptable, such as Cold, Heat, and Drug Resistance. Those would be things such as Insect, Water, Rodent, Air, etc. Transmissions are vectors, ways your disease spreads. Symptoms are things your disease does to people, whether it be coughing and sneezing or total organ failure. When I tell you to evolve X or Y, those are always found in the evolution menu under symptoms, transmissions, or abilities.
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